![]() The 1669676326 NPI number is assigned to the healthcare provider SAKTHIRAJ SUBRAMANIAN MD, practice location. In conclusion, we demonstrate a novel method of using MREs in the identification of functionally relevant mRNA-microRNA interactions in TN breast cancer. This webpage represents 1669676326 NPI record. Further analysis of MAPK gene regulatory networks revealed microRNA partners that influence and modulate MAPK signaling. Subree Subramanian, PhD Professor, Basic and Translational Research, Department of Surgery Contact Info. ReMIx identified candidate mRNAs and microRNAs in the MAPK signaling cascade. ![]() A genome-wide approach to comparative oncology: High-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations. One Stop MyU 2022 Regents of the University of Minnesota.All rights reserved. University of Minnesota researchers have developed an amplification method and library preparation process of pico-quantities of RNA. Angstadt AY, Thayanithy V, Subramanian S, Modiano JF, and Breen M. IP Status: Issued US Patent Application : Small RNA Profiling. We applied ReMIx to triple-negative (TN) breast cancer tumor-normal adjacent pairs and identified MREs specific to TN tumors. Small RNA Amplification and Library Preparation (20140020, Dr. We developed a bioinformatics method “ReMIx” that utilizes RNA sequencing (RNA-Seq) data to quantify MRE frequencies across the transcriptome. ![]() In this study, we leveraged MREs and their frequencies in cancer and matched normal tissues to obtain insights into disease-specific interactions between mRNAs and microRNAs. MicroRNAs binds to one or more microRNA response elements (MREs) located on the 3′UTR of mRNAs. The mRNA-microRNA interactions also determine the post-transcriptional availability of mRNAs and unbound microRNAs. ![]() Complex interactions between mRNAs and microRNAs influence cellular functions. Subree Subramanian (University of Minnesota, United States) 'Tumor Cell Secreted Extracellular Vesicles Regulate T Cell Priming and Regulate Immune Response in Colorectal Cancer' 12:15 pm - 12:20 pm: Discussion. ![]()
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